Virilizing Adrenal Adenoma with Studies on the Steroid Content of the Adrenal Venous Effluent and a Review of the Literature*

Abstract
THIS IS a report of a new instance of a patient with a virilizing adrenal adenoma in whom the steroid content of both adrenal venous effluents was assayed. In addition the study delineates the clinical and biochemical findings in the reported instances of virilizing adenoma including the available data on the steroid content of adrenal venous effluent. Pure virilizing adrenal adenoma in the adult female is a rare disorder. We have been able to collect only 34 such instances in the literature, including 3 of our own (1–30) (Table 1). For purposes of comparison, the details of the clinical features and biochemical values obtained in 18 reported children with virilizing adrenal adenoma (12, 31–45) (Table 2) are also presented, as well as some data on the adrenal venous effluent on all 8 adult female patients with pure virilizing adrenocortical carcinoma documented in the literature (9, 12, 46–49) (Table 3).

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