CORPUS LUTEUM ORGANOTHERAPY IN CLINICAL PRACTICE
Open Access
- 31 January 1914
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. LXII (5) , 359-362
- https://doi.org/10.1001/jama.1914.02560300017006
Abstract
Recent experimental and clinical investigations have determined and established the following important facts: The human ovary has an internal secretion. This internal secretion dominates menstruation and maintains pregnancy during the early months. Corpus luteum is the structure chiefly concerned and the probable source of the internal secretion. The corpus luteum of pregnancy is more stable than that of ovulation. Corpus luteum has a selective action on the endometrium and prepares the uterine mucosa for the reception of the ovum. The acme of development of corpus luteum is synchronous with the onset of menstruation. There is a distinct relationship between corpus luteum and the other internal secretory structures of the body. Removal of all lutean tissue is followed by cessation of the menstrual flow. Animal corpus luteum, when administeredKeywords
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