Has the Cancer Cell any Differential Characteristics?

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Abstract
In 1925 the following statement was made (8): “Both reparative regenerative and malignant regenerative cells possess one or more nucleoli but as a rule those of the malignant cell are much larger in proportion to the nucleus than those of the reparative cells.” This and the following statement were made after years of study with measurements of cells and their parts in perfectly fresh unfixed and unembedded tissues removed at surgical explorations and operations. In the same year (1925) it was also said (7): “The cancer cell may not always be distinguished from a normal regenerating cell, but this can be done frequently because there is a difference in the volume-relationship between nucleolus, nucleus and the whole cell in reparative regenerative cells and malignant regenerative cells” (Figs. 1, 2 and 3).

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