Effect of Nanonization on Absorption of 301029: Ex Vivo and In Vivo Pharmacokinetic Correlations Determined by Liquid Chromatography/Mass Spectrometry
- 1 January 2002
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 19 (8) , 1091-1096
- https://doi.org/10.1023/a:1019829622088
Abstract
Purpose. To compare Caco-2 monolayer permeability and in vivobioavailability of microparticle with nanoparticle 301029, a thiadiazole derivative, and to determine whether nanonization could improve...Keywords
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