• 1 October 1968
    • journal article
    • Vol. 3  (8) , 795-800
Abstract
Spleen and lymph node suspensions prepared from parental donor mice pretreated with four daily anti-lymphocyte serum (ALS) injections have been demonstrated to be incapable of inducing a graft-versus-host (GVH) syndrome when injected into F1 hybrid recipient mice. A single ALS injection to the parental donor renders thoracic duct lymphocytes incapable of inducing a GVH response but the activity of spleen cell suspensions is retained.