Synthesis of compounds active against HIV: preparation of 6′-fluorocarbocyclic AZT (AZT = 3′-deoxy-3′-azidothymidine)
- 1 January 1989
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 22,p. 1707-1709
- https://doi.org/10.1039/c39890001707
Abstract
The carbocyclic nucleosides (2) and (3) have been prepared and tested for anti-HIV activity: AZT-triphosphate (20)(AZT = 3′-deoxy-3′-azidothymidine) was synthesized by a new procedure and the same method was used to make the novel triphosphate (21).Keywords
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