Intracellular Magnesium Depletion in Chronic Renal Failure

Abstract
Skeletal-muscle magnesium, estimated as an index of body magnesium store, was significantly lower (p less than 0.05) in 12 patients with advanced chronic renal failure (most of whom showed hypermagnesemia) than in controls matched for sex and age. There is indirect evidence that renal insufficiency sets at a new level the control of magnesium gradient across the cell membrane.