Ligand-controlled self-assembly of polynuclear lanthanide–oxo/hydroxo complexes: from synthetic serendipity to rational supramolecular design
- 23 November 2001
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 24,p. 2521-2529
- https://doi.org/10.1039/b107971a
Abstract
Lanthanide ions and complexes occupy a special position in developing synthetic nucleases capable of catalyzing the hydrolytic cleavage of RNA or DNA. Stimulated by a number of serendipitous lanthanide complexes that feature the common active-site structure of dinuclear metallo-phosphodiesterases, rational design and synthesis of polynuclear lanthanide–hydroxo species via ligand-controlled hydrolysis of the lanthanide ions were attempted. The efforts yielded a series of highly sophisticated yet structurally well-defined lanthanide–hydroxo complexes. These materials are potentially applicable to the study of biomimetic catalysis of phosphate diester cleavage. Research highlights are described in this Feature Article.Keywords
This publication has 0 references indexed in Scilit: