Some aspects of the failure of sucrose tablets

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Abstract
The effects of compression force, amount of magnesium stearate, carbowax and talc on the failure characteristic of tablets of sucrose granulation with gum acacia as binder have been examined. The results show that breakage of the tablets during ejection is accompanied by high ejection forces and low ratio of lower to upper punch force. Tablets with an upper bevelled edge capped at high applied forces unlike those prepared with a flat upper face. This may be due to high radial forces in the bevelled top at the end of the compression cycle, caused by the bevelled edge, resulting in break-down of interparticulate bonds formed during compression. At very high compression forces all tablets showed lamination because of axial expansion.