Synthetic Study on Human C-Peptide and its Related Peptides
- 1 January 1981
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 362 (1) , 775-798
- https://doi.org/10.1515/bchm2.1981.362.1.775
Abstract
Syntheses of 18 peptides related to human C-peptide and the connecting peptide are described. The syntheses were performed exclusively by the azide fragment condensation method. The immunochemical results justified the utilization of these peptides for development of human C-peptide radioimmunoassay system. The synthetic peptide fragments may be extremely important substrates for assessment of specificity of human C-peptide antisera and thus usefulness of the antisera in practical measurement of blood levels of human C-peptide immunoreactivity.This publication has 14 references indexed in Scilit:
- Studies on Polypeptides, VII. Synthesis, Circular Dichroism and Immunological Studien of Tyrosyl C-Peptide of Human ProinsulinHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1975
- Synthesis of human connecting peptide derivatives and their immunological propertiesBiochemical and Biophysical Research Communications, 1974
- Polypeptides. LII. Synthesis of a cysteine protected peptide amide corresponding to positions 81-104 of the ribonuclease T1 sequenceJournal of the American Chemical Society, 1973
- Zur Synthese von Peptiden mit Eigenschaften des Human‐Proinsulin‐C‐Peptids (hC‐Peptid), VI. Darstellung der Gesamtsequenz des Human‐Proinsulin‐C‐Peptids und seines [Glu9, Gln11]‐AnalogenEuropean Journal of Inorganic Chemistry, 1973
- Studies on Polypeptides, IV. The Synthesis of C-Peptide of Human ProinsulinHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1973
- Synthesis of proinsulin. III. Synthesis of polypeptides related to the connecting peptide segment of bovine proinsulinJournal of the American Chemical Society, 1972
- Polypeptides. XLIX. Fragment condensations with peptide derivatives related to the primary structure of ribonuclease T1Journal of the American Chemical Society, 1971
- Aminosäure‐ und PeptidsemicarbazideEuropean Journal of Inorganic Chemistry, 1964
- The Use of Esters of N-Hydroxysuccinimide in Peptide SynthesisJournal of the American Chemical Society, 1964
- 728. Cyto-active amino-acids and peptides. Part VIII. Nα-acyl, amide, ester and peptide derivatives of melphalanJournal of the Chemical Society, 1960