High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
Open Access
- 1 March 2005
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 92 (5) , 891-894
- https://doi.org/10.1038/sj.bjc.6602436
Abstract
High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9–151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5–7.2). Thus, HPV load is a type-dependent risk marker for invasive carcinoma.Keywords
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