SILICONE LYMPHADENOPATHY - A REPORT OF 2 CASES, ONE WITH CONCOMITANT MALIGNANT-LYMPHOMA

  • 1 January 1982
    • journal article
    • research article
    • Vol. 5  (2) , 133-141
Abstract
Two cases of axillary lymphadenopathy induced by foreign body reaction to silicone particles are presented. Both were patients with longstanding arthritis who had silastic metacarpophalangeal joint implants; 1 patients had concomittant lymphoma. The material was conclusively identified as silicone by EM analysis. With currently increasing numbers of silastic finger joint arthroplasties performed for rheumatoid arthritis, silicone lymphadenopathy should be considered in the differential diagnosis of axillary node enlargement in these patients. A history of previous silastic arthroplasty may not always be made available to the pathologist but the histological appearances are sufficiently characteristic to warrant this history being sought.

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