Degradation of missense mutant β-galactosidase proteins in Escherichia coli K-12
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 164 (1) , 105-108
- https://doi.org/10.1007/bf00267605
Abstract
Ten out of 43 missense mutations in the lacZ gene of Escherichia coli gave rise to polypeptide chains that were degraded in vivo. While many of the mutants appeared to be fully or partially CRM−, there appeared to be no obvious correlation between degradation, map position, altered subunit association and the half-life of the mutant proteins.This publication has 21 references indexed in Scilit:
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