The "Decline and Fall" of Nontyphoidal Salmonella in the United Kingdom
Open Access
- 19 November 2012
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 56 (5) , 705-710
- https://doi.org/10.1093/cid/cis967
Abstract
Remarkable changes in the epidemiology of human nontyphoidal salmonellosis have occurred in the United Kingdom over the last century. Between 1981 and 1991, the incidence of nontyphoidal salmonellosis in the United Kingdom rose by >170%, driven primarily by an epidemic of Salmonella enterica subspecies enterica serovar Enteritidis phage type (PT) 4, which peaked in 1993. Measures introduced to control this epidemic included legislation, food safety advice, and an industry-led vaccination program in broiler-breeder and laying poultry flocks. The incidence of Salmonella Enteritidis has been falling since 1997, and levels of Salmonella Enteritidis PT4 have fallen to preepidemic levels and have stayed low. The temporal relationship between vaccination programs and the reduction in human disease is compelling and suggests that these programs have made a major contribution to improving public health.Keywords
This publication has 42 references indexed in Scilit:
- Changes in Causes of Acute Gastroenteritis in the United Kingdom Over 15 Years: Microbiologic Findings From 2 Prospective, Population-Based Studies of Infectious Intestinal DiseaseClinical Infectious Diseases, 2012
- Source attribution of human salmonellosis using a meta-analysis of case-control studies of sporadic infectionsEpidemiology and Infection, 2011
- Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practiceGut, 2011
- The Relationship Between the Numbers of Salmonella Enteritidis, Salmonella Heidelberg, or Salmonella Hadar Colonizing Reproductive Tissues of Experimentally Infected Laying Hens and Deposition Inside EggsAvian Diseases, 2011
- Application of Bayesian Techniques to Model the Burden of Human Salmonellosis Attributable to U.S. Food Commodities at the Point of Processing: Adaptation of a Danish ModelFoodborne Pathogens & Disease, 2011
- Foodborne Illness Acquired in the United States—Major PathogensEmerging Infectious Diseases, 2011
- Description and Burden of Travel‐Related Cases Caused by Enteropathogens Reported in a Canadian CommunityJournal of Travel Medicine, 2010
- Source attribution of human Salmonella cases in SwedenEpidemiology and Infection, 2010
- Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathwaysGenome Research, 2008
- Salmonella control—past, present and futureAvian Pathology, 1993