A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration
Open Access
- 1 May 1999
- journal article
- research article
- Published by Elsevier
- Vol. 23 (1) , 181-192
- https://doi.org/10.1016/s0896-6273(00)80764-3
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansionNature Genetics, 1997
- Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in BrainScience, 1997
- Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotypeHuman Molecular Genetics, 1996
- Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic MiceCell, 1996
- A huntingtin-associated protein enriched in brain with implications for pathologyNature, 1995
- Neuronal loss in the hippocampus in Huntington's disease: a comparison with HIV infection.Journal of Neurology, Neurosurgery & Psychiatry, 1993
- A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomesCell, 1993
- Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiationNeuron, 1992
- Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic TransmissionScience, 1988
- Selective Sparing of a Class of Striatal Neurons in Huntington's DiseaseScience, 1985