Plasma Antihemophilic Activity Following Total Body Irradiation.

Abstract
Thrombocy-topenia and impairment in prothrombin conversion was produced in 10 dogs with ionizing irradiation. The antihemophilic factor was assayed by in vitro and in vivo procedures and remained at normal levels. Hemophilic blood cells corrected the irradiation clotting defect in vitro.