Narcotic Addiction, Physical Dependence and Relapse

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Abstract
THE pioneering studies of Spragg, Wikler, Martin, Nichols, Beach, Weeks, Khazan, Seevers, Denau, Schuster, Thompson and their associates during the past 20 years have provided experimental models of narcotics addiction. Recent and authoritative reviews1 2 3 4 5 6 7 8 9 10 of these studies are available, and need not be repeated here in detail. Instead, what will be attempted in the present review is to look at the experimental work on addiction in animals with the eye of a clinician who is concerned with the human problem of narcotics abuse, and ask what can be learned from the laboratory studies about the prevention and treatment of the . . .