Some Characteristics of Certain Reflexes Which Modify the Circulation in Man

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Abstract
Records are presented which have been obtained from man by direct intra-arterial catheterization and electrocardiography. These records have been selected (1) because they offer evidence for the validity of Starling's law in intact man and (2) because they demonstrate that when the heart is influenced by activity of the so-called "intrinsic" reflexes these manifestations of Starling's law are modified. It appears from these types of data that ventricular activity may be directly affected independently of influences upon the pacemakers of the heart.