Another Case of Transfusion-Related Lung Injury due to Anti-HNA-3a (-5b)
- 1 July 2000
- journal article
- Published by S. Karger AG in Transfusion Medicine and Hemotherapy
- Vol. 27 (4) , 208-210
- https://doi.org/10.1159/000025273
Abstract
Following a literature review, we describe a fourth case of transfusion-related lung injury (TRALI) due to a leukocyte antibody with anti-HNA-3a (-5b) specificity. The patient, a 72-year-old male, was admitted to hospital for surgery following an abdominal aortic aneurysm. Postoperatively, after transfusion of 2 units of packed red blood cells (PRBC) and 2 units of fresh frozen plasma (FFP) concentrate, the patient developed typical signs of TRALI. Anti-HNA-3a was found in the serum of 1 of the 2 FFP units. The female donor had no transfusion history, but had had 2 pregnancies more than 35 years previously.Keywords
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