The influence of Nematospiroides dubius on subsequent Nippostrongylus brasiliensis infections in mice
- 1 October 1975
- journal article
- research article
- Published by Cambridge University Press (CUP) in Parasitology
- Vol. 71 (2) , 349-355
- https://doi.org/10.1017/s0031182000046783
Abstract
The fecundity and longevity of Nippostrongylus brasiliensis was prolonged in mice previously infected with Nematospiroides dubius only when the former developed from the larval stage in those mice. Such worms appeared to be less immunogenic than worms which developed in mice never exposed to N. dubius.It is proposed that prolonged fecundity and longevity resulted from an adaptation undertaken by the worms in the face of host antibodies which had been developed against the pre-existing N. dubius infection.Keywords
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