Detection of auto-immune antibody and tissue antigens by the `microspot' technique

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Abstract
A new specific antigen-antibody precipitation technique, the "microspot" test, detected the antibody arising spontaneously in auto-immune thyroiditis. The technique can detect low levels of both the auto-immune antibody and the antigen against which it is directed. It is suggested that the technique could usefully be extended to the study of other proven or suspected auto-immune conditions.