Cell-Mediated Cytotoxic Response to Cells Bearing Marek's Disease Tumor-Associated Surface Antigen in Chickens Infected With Marek's Disease Virus
- 1 June 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 58 (6) , 1647-1651
- https://doi.org/10.1093/jnci/58.6.1647
Abstract
In a microcytotoxicity test in which 51Cr-labeled cells of a Marek's disease (MD) lymphoblastoid line {MSB-1 line) were used, cell-mediated cytotoxicity of spleen cell suspensions prepared from chickens inoculated with MD virus was demonstrated. This cytotoxic response, presumably directed against MD tumor-associated surface antigen, was detectable briefly after virus infection and paralleled the appearance of early lymphoproliferative lesions characteristic of MD.Keywords
This publication has 0 references indexed in Scilit: