Amydopyrine Pancytopenia: Detection of Leucocytotoxic Antibodies by a 51Cr-Release Test
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 61 (1) , 52-54
- https://doi.org/10.1159/000207626
Abstract
Amydopyrine is known to cause agranulocytosis by an immunological mechanism [2]. However, pancytopenia due to amydopyrine is extremely rare and usually mild and transient [3]. This report describes a patient with severe pancytopenia presumably due to amydopyrine sensitivity. Granulocytotoxic and lymphocytotoxic antibodies were detected in the patient’s serum using a 51Cr-release test.Keywords
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