Efficient copper (II)-mediated nuclease activity of ortho-quinacridines
- 1 January 1998
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 21,p. 2349-2350
- https://doi.org/10.1039/a806095i
Abstract
The ortho-quinacridine compounds OQ1 and OQ2 bind strongly to double stranded DNA and effect efficient cleavage in the presence of Cu2+ and in the absence of reducing agent; their activity increases further in the presence of hydrogen peroxide.Keywords
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