Therapeutic activity of ceftazidime and eleven other β-lactam antibiotics against experimental Haemophilus influenzae, type b meningitis
- 1 May 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 13 (5) , 517-520
- https://doi.org/10.1093/jac/13.5.517
Abstract
Twelve β-lactams (11 cephalosporins and aztreonam) were compared in an infant rat model of Haemophilus influenzae, type b meningitis. Ceftazidime was the most effective compound tested and showed greater activity than cefuroxime, lata-moxef (moxalactam) and cefotaxime—all of which have been used successfully in clinical haemophilus meningitis in children.Keywords
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