Non-random Karyotype Progression in Chronic Myeloid Leukaemia
- 1 January 1967
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 12 (3) , 219-226
- https://doi.org/10.1080/09553006714550741
Abstract
A case of chronic myeloid leukaemia is reported, which in the past had been given a therapeutic dose of 131I for thyrotoxicosis. Cytogenetic studies performed shortly before death showed a stem-cell chromosome number 49(2PH1 and 2C9) and a sufficient number of 47 and 48 cells to suggest an evolutionary pattern. The possible role of the 131I therapy is discussed.Keywords
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