Total synthesis of the protoberberine alkaloid (–)-xylopinine by photochemical 1,3-asymmetric induction

Abstract
The protoberberine alkaloid, xylopinine (12), has been synthesised in an optically active form, a key reaction being the photochemical cyclisation of optically active 1,2,3,4-tetrahydro-6,7-dimethoxy-3-methoxycarbonyl-1-methylene-2-veratrolisoquinoline (4) with 1,3-asymmetric induction.

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