Copper Accumulation in Patients Undergoing Chronic Hemodialysis. The Role of Cuprophan

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Abstract
After each hemodialysis treatment using ethylene oxide sterilized Cuprophan as the dialysis membrane, plasma copper concentration increases. Blood plasma extracts copper from Cuprophan and liver copper is elevated in patients on maintenance hemodialysis using Cuprophan prepared by the aforementioned technique. The clinical consequences of this copper accumulation are uncertain.

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