Epidermal Growth Factor Receptor Internalization through Clathrin‐Coated Pits Requires Cbl RING Finger and Proline‐Rich Domains But Not Receptor Polyubiquitylation
- 1 July 2003
- Vol. 4 (8) , 529-543
- https://doi.org/10.1034/j.1600-0854.2003.t01-1-00109.x
Abstract
Cbl proteins have been implicated in the regulation of endocytic trafficking of epidermal growth factor receptor. However, the precise role of Cbl in epidermal growth factor receptor endocytosis is n...Keywords
This publication has 36 references indexed in Scilit:
- Signal transduction and endocytosis: close encounters of many kindsNature Reviews Molecular Cell Biology, 2002
- Effect of Tyrosine Kinase Inhibitors on Clathrin-coated Pit Recruitment and Internalization of Epidermal Growth Factor ReceptorJournal of Biological Chemistry, 2002
- A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signalingThe EMBO Journal, 2002
- A New Ticket for Entry into Budding Vesicles—UbiquitinCell, 2001
- Polyubiquitination of the Epidermal Growth Factor Receptor Occurs at the Plasma Membrane upon Ligand-induced ActivationJournal of Biological Chemistry, 2000
- Tyrosine kinase activity of the EGF receptor is enhanced by the expression of oncogenic 70Z-CblOncogene, 1997
- Lysosomal Targeting of Epidermal Growth Factor Receptors via a Kinase-dependent Pathway Is Mediated by the Receptor Carboxyl-terminal Residues 1022-1123Journal of Biological Chemistry, 1996
- Tyrosine Phosphorylation of Cbl upon Epidermal Growth Factor (EGF) Stimulation and Its Association with EGF Receptor and Downstream Signaling ProteinsJournal of Biological Chemistry, 1996
- Ubiquitination of a Yeast Plasma Membrane Receptor Signals Its Ligand-Stimulated EndocytosisCell, 1996
- Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.The Journal of cell biology, 1994