Applications of the Redy® Sorbent System to Hemodialysis and Peritoneal Dialysis

Abstract
The application of sorbent technology to the treatment of uremia has been limited by the inability to adsorb urea adequately. Conversion of urea to ammonium carbonate and adsorption by zirconium phosphate provides a practical means of removing urea. This combination, together with hydrated zirconium oxide and C, removes uremic waste products from dialysate. Over 1500 patients are undergoing maintenance hemodialysis with this system. The dialysate composition can be modified for the treatment of patients with acute renal failure. This sorbent system is now being used for the regeneration of peritoneal dialysate. Patients [20] have undergone a total of 90 dialyses, each of 4 to 24 h duration. One home patient has been solely on this system for 2 mo. The application of sorbent technology to peritoneal dialysis may be the most promising approach to a wearable dialysis system.

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