Effects of Sublingual Administration of Nitroglycerin on Pulmonary-Artery Pressure in Patients with Failure of the Left Ventricle

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Abstract
CHEST discomfort associated with paroxysmal nocturnal dyspnea is frequently quite distressing, and some patients describe this discomfort as pain.1 During the past several years, we have noted in the outpatient cardiac clinic of Freedmen's Hospital that patients have reported immediate relief of this chest discomfort, as well as the associated dyspnea, after sublingual administration of nitroglycerin. As a result of this, we were led to study the effect of sublingual administration of nitroglycerin on the pulmonary-artery pressure in patients with failure of the left ventricle. A preliminary statement of this effect has been published earlier from this laboratory.2 This paper . . .

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