Expression of epidermal growth factor receptor in human glioblastoma multiforme
- 1 January 1993
- journal article
- research article
- Published by Taylor & Francis in British Journal Of Neurosurgery
- Vol. 7 (3) , 261-265
- https://doi.org/10.3109/02688699309023808
Abstract
The expression of epidermal growth factor receptor was determined in a series of 88 patients with glioblastoma multiforme using a monoclonal antibody to the receptor. Positive staining was seen in 17 patients but this did not have prognostic significance when compared with known clinical prognostic factors using a computer model. The significance of receptor expression in these tumours is discussed.Keywords
This publication has 20 references indexed in Scilit:
- Gene Amplification in Malignant Human Gliomas: Clinical and Histopathologic AspectsJournal of Neuropathology and Experimental Neurology, 1988
- Epidermal Growth Factor Binding in Intracranial Neoplasms: Preliminary biochemical and clinicopathological findingsBritish Journal Of Neurosurgery, 1988
- Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma.Proceedings of the National Academy of Sciences, 1986
- Association of Multiple Copies of the N-mycOncogene with Rapid Progression of NeuroblastomasNew England Journal of Medicine, 1985
- N-MYC AMPLIFICATION IN MALIGNANT ASTROCYTOMAThe Lancet, 1985
- Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial originNature, 1985
- Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequencesNature, 1984
- Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumourNature, 1983
- CELLULAR ONCOGENES AND RETROVIRUSESAnnual Review of Biochemistry, 1983
- Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7.Proceedings of the National Academy of Sciences, 1980