Clearance of lead-212 ions from rabbit bronchial epithelium to blood
- 1 September 1977
- journal article
- research article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 22 (5) , 932-948
- https://doi.org/10.1088/0031-9155/22/5/013
Abstract
The 212Pb ions were introduced by intubation either into the trachea or into smaller, more distal bronchi. Removal from lung was followed by external gamma -counting. Mucociliary clearance to the GI tract was blocked by tracheostomy. Two distinct phases of clearance from bronchial epithelium to blood were observed. Approximately 20% of deposited 212Pb is rapidly absorbed with a half-time of about 4 min, the remainder with a biological half-time of about 9 h, irrespective of the site of instillation in the bronchial tree.This publication has 10 references indexed in Scilit:
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