Susceptibility of human and murine Chlamydia trachomatis serovars to granulocyte‐ and epithelium‐derived antimicrobial peptides
- 1 May 2003
- journal article
- Published by Wiley in Chemical Biology & Drug Design
- Vol. 61 (5) , 237-242
- https://doi.org/10.1034/j.1399-3011.2003.00053.x
Abstract
Four antimicrobial peptides, protegrin-1, RTD-1, cryptdin-4, and indolicidin, were tested for their ability to inhibit the in vitro growth of Chlamydia trachomatis serovars E, L2, and mouse pneumonitis (MoPn). In general, protegrin-1 was found to have the strongest anti-chlamydial activity. Overall, of the three serovars tested, L2 was the most susceptible while MoPn was the most resistant to these peptides.Keywords
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