Fatal Paracetamol Poisoning in an Epileptic

1 January 1988

journal article
research article
Published by SAGE Publications in Human Toxicology

Vol. 7 (1) , 33-34
https://doi.org/10.1177/096032718800700106

Abstract

Treatment nomograms are used in paracetamol poisoning for indicating when antidotes should be given to prevent hepatic or renal damage.¹ We report a fatal case of paracetamol poisoning in an epileptic taking phenytoin, in whom no antidotal treatment was given because it was not indicated.

Keywords

This publication has 10 references indexed in Scilit:

Paracetamol Toxicity: is Enzyme Induction Important?
Human Toxicology, 1986
Lethal enhancement of therapeutic doses of acetaminophen by alcohol
Digestive Diseases and Sciences, 1986
Dissociation of cell death from covalent binding of paracetamol by flavones in a hepatocyte system
Biochemical Pharmacology, 1982
Treatment of Acetaminophen Poisoning
Archives of internal medicine (1960), 1981
Effect of acetaminophen (paracetamol) and its antagonists on glutathione (GSH) content in rat liver
Biochemical Pharmacology, 1980
Intravenous N-acetylcystine: the treatment of choice for paracetamol poisoning.
BMJ, 1979
Evidence for the involvement of N-ACETYL-p-quinoneimine in acetaminophen metabolism
Biochemical Pharmacology, 1979
CYSTEAMINE, METHIONINE, AND PENICILLAMINE IN THE TREATMENT OF PARACETAMOL POISONING
The Lancet, 1976
Potentiation by Previous Drug Therapy of Hepatotoxicity following Paracetamol Overdosage
Scottish Medical Journal, 1973