AGE CHANGES IN THE HISTOLOGY OF THE HUMAN PITUITARY

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Abstract
The male pituitary increases gradually from birth to the age of 20 years. In girls there is accelerated growth during the teens. After 20 years the weight is fairly constant except in the pregnant female. In the older age group there is a slight decrease. In adults basophiles are more abundant in the male than in the female, but for eosinophiles the reverse is true. Follicular concretions are numerous in late fetal life, decrease postnatally but increase greatly in old age. Mesothelial concretions and associated mesothelium are abundant in old age. The occurrence of cilia, cysts and tubular glands are cited. Lymphocytes and lymphoid tissue had a high incidence in all age groups over 5 years of age. They occurred twice as often in the male than in the female. Tumorettes were found to develop from epithelium and from nervous tissue. The incidence was nearly the same in the 2 sexes.