Cellular Toxicity and Mutagenicity Assays from On-Site Sampling of Drinking Water Treatment Plants Using Multistage Ozonation

1 June 1987

journal article
research article
Published by Taylor & Francis in Ozone: Science & Engineering

Vol. 9 (3) , 179-193
https://doi.org/10.1080/01919518708552334

Abstract

Studies were carried out on-site in a potable water production plant utilizing ozonation treatment at three stages of the process. The quality of water in the treatment line was studied by chemical analysis, but also for toxicity to Hela cells after XAD resin concentration, and for mutagenesis to Salmonella Ames strains and mammalian cells V79 HGPRT system. With a sufficient dose of ozone and activated carbon adsorption, the initial cytotoxicity of the raw water and the mutagenic or promoter activity are destroyed.

Keywords

This publication has 13 references indexed in Scilit:

Rapidity of RNA synthesis in human cells
Water Research, 1985
The use of XAD-resins for the detection of mutagenic activity in water
Chemosphere, 1981
The use of XAD-resins for the detection of mutagenic activity in water
Chemosphere, 1981
Evaluation of public health aspects of carcinogenic/mutagenic biorefractories in drinking water
Preventive Medicine, 1980
The HPRT locus
Cell, 1979
Mutagenicity of ozonated, recycled water
Bulletin of Environmental Contamination and Toxicology, 1978
Biomedical Aspects of Biorefractories in Water
Published by Elsevier ,1978
Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test
Mutation Research/Environmental Mutagenesis and Related Subjects, 1975
Mammalian cell transformation and cell-mediated mutagenesis by carcinogenic polycyclic hydrocarbons
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1975
Cell-mediated mutagenesis of mammalian cells with chemical carcinogens
International Journal of Cancer, 1974