Use of Bordetella pertussis BP3385 To Establish a Cutoff Value for an IS 481 -Targeted Real-Time PCR Assay

Abstract
This study utilized the Bordetella pertussis single-copy PCR target BP3385 as a means of confirming IS481 PCR-positive reactions with cycle threshold (C(T)) values of >35. IS481 PCRs with C(T) values of >35 cycles may represent PCR conditions where there is <1 CFU of B. pertussis per PCR.