Cyclosporine vs Tacrolimus Therapy for Posterior and Intermediate Uveitis

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Abstract
Cyclosporine is an effective treatment for noninfectious posterior and intermediate uveitis and is now in widespread use in cases where prednisolone therapy has failed.1-3 However, enthusiasm is tempered by its toxic effect profile, which includes renal impairment, systemic hypertension, and metabolic abnormalities. Furthermore, it is estimated that approximately 20% of patients with uveitis are refractory to cyclosporine, indicating the need to evaluate more potent and safer treatment strategies.4