An Investigation of Clinical Correlates of Lewy Bodies in Autopsy-Proven Alzheimer Disease
Open Access
- 1 March 2001
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 58 (3) , 460-465
- https://doi.org/10.1001/archneur.58.3.460
Abstract
AS MANY AS one third to half of patients diagnosed as having Alzheimer disease (AD) have concomitant Lewy bodies (LBs) when examined at autopsy. Several studies have asked whether, in patients who meet clinical and pathologic criteria for AD, there are unique or additional clinical features associated with the presence of LBs.1-9 The clinical features of interest are those that have been associated with dementia with Lewy bodies (DLB), including extrapyramidal signs (EPS) and psychiatric features (especially visual hallucinations).10 The findings to date have been inconsistent. The present study was designed to address this issue, using patients from the Predictors Study.11Keywords
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