VALIDITY OF MEASURING REGIONAL PULMONARY ARTERIAL BLOOD FLOW WITH MACROAGGREGATES OF HUMAN SERUM ALBUMIN

Abstract
Evidence for the validity of the MAA method in the determination of regional pulmonary arterial blood flow is: (a) sizes of the particles are optimal; (b) extraction efficiency is high; (c) uniform mixing of the particles is complete prior to their arrival at the lungs; (d) the distribution of the macroaggregates and the red blood cells is similar; (e) correlation with differential spirometry in man at rest and during exercise is good; and (f) the known effects of erect posture and phasic variation of the respirators' cycle on the pattern of distribution of pulmonary blood flow in man were clearly demonstrated.