Large-Scale Synthesis of Enantio- and Diastereomerically Pure (R,R)-Formoterol

This publication has 12 references indexed in Scilit:

• The role of 4-(3-phenylpropyl)pyridine N-Oxide (P3NO) in the manganese-salen-catalyzed asymmetric epoxidation of indene
  Tetrahedron Letters, 1996
• β-Adrenergic Bronchodilators
  New England Journal of Medicine, 1995
• Salmeterol
  Medicinal Research Reviews, 1995
• Enantioselective synthesis of salmeterol via asymmetric borane reduction
  Tetrahedron Letters, 1994
• cis-1-amino-2-indanol in asymmetric synthesis. Part I. A practical catalyst system for the enantioselective borane reduction of aromatic ketones
  Tetrahedron Letters, 1994
• A practical process for the preparation of tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole-borane. A highly enantioselective stoichiometric and catalytic reducing agent
  The Journal of Organic Chemistry, 1993
• Biological significance of the enantiomeric purity of drugs
  Chirality, 1993
• Steric aspects of agonism and antagonism at β‐adrenoceptors: Synthesis of and pharmacological experiments with the enantiomers of formoterol and their diastereomers
  Chirality, 1991
• Absolute configurations of four isomers of 3-formamido-4-hydroxy-.ALPHA.-[[N-(p-methoxy-.ALPHA.-methylphenethyl)amino]methyl]benzyl alcohol, a potent .BETA.-adrenoreceptor stimulant.
  CHEMICAL & PHARMACEUTICAL BULLETIN, 1978
• Adrenergic agents. 1. Synthesis and potential .beta.-adrenergic agonist activity of some catechol amine analogs bearing a substituted amino functionality in the meta position
  Journal of Medicinal Chemistry, 1974