An Enantioselective Chemoenzymatic Synthesis of the Four 1-Amino 2-Methylcyclopropane Carboxylic Acids

Abstract
Racemic 2-methylcyclopropane dicarboxylic acid dimethyl ester undergoes selective enzymatic reactions to give enantiomerically pure monocarboxylic acids which by classical organic chemistry lead to the four 1-amino 2-methyl cycloproane carboxylic acids.