5′-Amino Acid Esters of Antiviral Nucleosides, Acyclovir, and AZT Are Absorbed by the Intestinal PEPT1 Peptide Transporter
- 1 January 1998
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 15 (8) , 1154-1159
- https://doi.org/10.1023/a:1011919319810
Abstract
Purpose. General use of nucleoside analogues in the treatment of viral infections and cancer is often limited by poor oral absorption. Valacyclovir, a water soluble amino acid ester prodrug of...Keywords
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