Pathogenesis of Urinary-Tract Infections in Children

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Abstract
DURING the past decade there has been a revival of interest in the subject of childhood urinary-tract infection, stimulated in part by the realization that these infections are not always merely isolated events but often the forerunners of serious renal disease of adulthood. This renewal has, in fact, been so extensive that new information has accumulated faster than it can readily be exploited clinically. In this review, an attempt is made to assemble some of this material and to evaluate its significance in relation to the basic pathogenesis and natural history of the disease.Clinical DataDefinitionRecent discoveries have . . .