STUDIES IN SO-CALLED WATER INTOXICATION

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Abstract
Following in general the procedure of Rowntree and others, the ingestion of water was forced in dogs by the use of a stomach tube. Ataxia, twitching, prostration, convulsions, and in some cases death, resulted. It could be shown that these symptoms were more closely associated with a lowering of the blood chloride than with hemodilution or retention of water in the body. The loss of chloride was chiefly due to loss of gastric juice by vomiting and led to an alkalosis. It could not be shown that non-electrolytes increased in the blood to compensate osmotically for the electrolyte reduction.

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