Autologous Mixed Lymphocyte Reaction in Man.
- 1 February 1983
- Vol. 38 (2) , 113-118
- https://doi.org/10.1111/j.1398-9995.1983.tb01594.x
Abstract
The proliferative response of T lymphocyte cultured with autologous non-T lymphocyte is known as the autologous mixed lymphocyte reaction (AMLR). In AMLR, both helper and suppressor functions are generated. T cell proliferative responses were examined in AMLR in 12 patients with bronchial asthma. Patients (10) with allergic rhinitis, and patients (10) with atopic dermatitis and comapred that with simultaneously studied healthy controls. The T cell proliferation in AMLR in patients with bronchial asthma was significantly higher than that of healthy normals. AMLR response in patients with allergic rhinitis or atopic dermatitis was comparable to controls. Mechanisms for increased AMLR in patients with bronchial asthma are discussed.Keywords
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