Retained folates in the rat
- 15 June 1977
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 164 (3) , 601-605
- https://doi.org/10.1042/bj1640601
Abstract
The retention of radioactivity after doses of 14C- and 3H-labelled folic acid is described. Radioactivity was retained in liver, kidney and gut of rats for some time after administration of the dose. The retained radioactivity could not be displaced by large doses of unlabelled folic acid or unlabelled 5-methyltetrahydrofolate. 14C- and 3H-labbelled folates showed similar chromatographic behaviour onion-exchange chromatography to 5-methyltetrahydrofolate, and on ion-exchange and gel-permeation chromatography to synthetic pteroylhepta-gamma-glutamate.This publication has 19 references indexed in Scilit:
- RAT BRAIN FOLATE IDENTIFICATIONJournal of Neurochemistry, 1976
- High-Molecular-Weight Folates of Rat LiverBiochemical Society Transactions, 1976
- Synthesis and breakdown of natural folates (folate polyglutamates).1975
- The identification of the forms of folate found in the liver, kidney and intestine of the monkey and their biosynthesis from exogenous pteroylglutamate (folic acid)Biochimica et Biophysica Acta (BBA) - General Subjects, 1974
- Effect of Methionine on Specific Folate Coenzyme Pools in Vitamin B12 Deficient and Supplemented RatsJournal of Nutrition, 1973
- The pH-dependent rearrangements of formyltetrahydrofolates and their nutritional implicationsBritish Journal of Nutrition, 1972
- Hydroxylated derivatives of 5-methy-5,6,7,8-tetrahydrofolateBiochemistry, 1971
- A convenient method for the preparation of dl-5-Methyltetrahydrofolic acid (dl-5-methyl-5,6,7,8-tetrahydropteroyl-l-monoglutamic acid)Analytical Biochemistry, 1970
- Naturally occurring folates in the blood and liver of the ratAnalytical Biochemistry, 1965
- The reaction of tetrahydropteroylglutamic acid and related hydropteridines with formaldehydeBiochemical Journal, 1959