TRAMADOL-INFUSION ANESTHESIA WITH SUBSTITUTION OF ENFLURANE AND VARIOUS NITROUS-OXIDE CONCENTRATIONS

  • 1 January 1985
    • journal article
    • research article
    • Vol. 34  (1) , 20-27
Abstract
The synthetic opioid tramadol was given to 40 patients during surgery according to a fixed, calculated infusion scheme. Anesthesia was started with thiopental and the patients were given different N2O concentrations via a semi-open system (group 1: 60%, group 2: 75%). The aim of this study was to clarify whether this anesthetic procedure was practicable or whether it had grave disadvantages in comparison with the anesthesia models used so far. It was investigated whether in this infusion scheme the proportion of N2O in the inspiratory mixture is sufficient or whether higher concentrations were required. In 24 of 40 patients analgesia or the depth of anesthesia was insufficient so that additional enflurane application was neccessary. Postoperative respiratory depression in 3 patients had to be treated with naloxone. The advantages of this procedure are the safe and easy practicability, absence of significant changes in the hemodynamic parameters, good postoperative response of the patients and postoperative pain relief as well as the low incidence of postoperative side effects such as nausea, vomiting and CO2-retention.