The Type 1 Diabetes Genetics Consortium
- 1 October 2006
- journal article
- review article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 1079 (1) , 1-8
- https://doi.org/10.1196/annals.1375.001
Abstract
The Type 1 Diabetes Genetics Consortium (T1DGC) is an international, multicenter program organized to promote research to identify genes and their alleles that determine an individual's risk for type 1 diabetes (T1D). The primary goal of the T1DGC is to establish resources and data that can be used by, and that is fully accessible to, the research community in the study of T1D. All the information on T1DGC can be accessed at the following web address: http://www.t1dgc.org. A resource base of well-characterized families is being assembled that will facilitate the localization and characterization of T1D susceptibility genes. From these families, the T1DGC is establishing banks of DNA, serum, plasma, and cell lines, as well as useful databases. The T1DGC also sponsors training opportunities (bioinformatics) and technology transfer (HLA genotyping).Keywords
This publication has 26 references indexed in Scilit:
- Localization of a Type 1 Diabetes Locus in the IL2RA/CD25 Region by Use of Tag Single-Nucleotide PolymorphismsAmerican Journal of Human Genetics, 2005
- A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetesNature Genetics, 2004
- Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune diseaseNature, 2003
- Genetics of type 1 diabetes mellitusGenes & Immunity, 2002
- A Genomewide Scan for Type 1–Diabetes Susceptibility in Scandinavian Families: Identification of New Loci with Evidence of InteractionsAmerican Journal of Human Genetics, 2001
- Evidence for oligogenic inheritance of type 1 diabetes in a large Bedouin Arab family.Journal of Clinical Investigation, 1998
- Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21Human Molecular Genetics, 1997
- Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8Human Molecular Genetics, 1996
- Susceptibility to Insulin-Dependent Diabetes Mellitus Maps to a Locus (IDDM11) on Human Chromosome 14q24.3–q31Genomics, 1996
- HL-A ANTIGENS AND DIABETES MELLITUSThe Lancet, 1974